- Facile one-pot synthesis of novel ortho-aminocarbonitriles and dicyanoanilines fused to heterocycles via pseudo four-component reactions
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1-Methylpiperidin-4-one and its sulfur and oxygen analogues undergo individual facile pseudo four-component reactions with two folds of malononitrile and various aldehydes by using ultrasonic irradiation and deficient quantities of pyrrolidine. As a conse
- Mojtahedi, Mohammad M.,Pourabdi, Ladan,Abaee, M. Saeed,Jami, Hamed,Dini, Masoud,Halvagar, Mohammad R.
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p. 1699 - 1705
(2016/03/08)
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- Synthesis of tetrahydroisoquinoline derivatives and evaluation of their anti-breast cancer activity
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Four novel tetrahydroisoquinoline derivatives 1–4 were synthesized and characterized by IR, 1H NMR, HRMS, and single crystal X-ray crystallography. Anticancer effect of the products were studied on five human breast cancer cell lines including
- Zhang,Yu,Ding,He,Zou
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p. 1430 - 1433
(2016/08/10)
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- A SPONTANEOUS RING CLOSURE REACTION AS A NEW ROUTE TO ISOQUINOLINE DERIVATIVES
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A spontaneous reaction takes place between benzaldehydes, malononitrile and N-methyl-4-piperidone to yield the compounds 1a-i which can be aromatized to the new dicyano-1,2,3,4-tetrahydroisoquinolinamines 2a-e.Tetrahydro-2,7-naphtyridines 3a,b were also i
- Andresen, Ole Riis,Pedersen, Erik B.
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p. 1467 - 1471
(2007/10/02)
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