CONVERGENT SOLID PHASE PEPTIDE SYNTHESIS. I. SYNTHESIS OF PROTECTED SEGMENTS ON A HYDROXYMETHYLPHENYLOXYMETHYL RESIN USING THE BASE LABILE FMOC α-AMINE PROTECTION. MODEL SYNTHESIS OF LHRH.
Convergent solid phase peptide synthesis has been applied to yield LHRH.The segments 1-6 and 7-10 of LHRH were synthesized on a hydroxymethylphenoxymethyl resin using the base labile Fmoc protecting group on the α-amines.The side chains were protected by
Pedroso, E.,Grandas, A.,Saralegui, M. A.,Giralt, E.,Granier, C.,Rietschoten, J. van
p. 1183 - 1192
(2007/10/02)
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