cas 83395-25-9, methyl N-[4-(3,6-dihydro-2H-pyridin-1-yl)-8-oxo-9-oxa-1,3,7-triazabicy clo[4.3.0]nona-2,4,6-trien-2-yl]carbamate

Articles about 83395-25-9Total 2 be found

61. Synthesis of 2-Oxo-2H-oxadiazolo-pyrimidine-5-carbamates
Thermal cyclization of the pyrimidine-N-oxide dicarbamate 2 gives a 95:5 mixture of the 2-oxo-2H-oxadiazolo- and pyrimidinecarbamates 3 and 4.An efficient procedure for the conversion of 3 to 4, and vice versa, is described.
Hengartner, Urs,Muller, Jean-Claude,Ramuz, Henri
p. 669 - 672
(2007/10/02)

7[3,6-Dihydro-1(2H)-pyridyl]-2-oxo-2H-[1,2,4]oxadiazolo[2,3-c]pyrimidine-5-carbamate compounds
Oxadiazolo[2,3-c]pyrimidine derivatives of the formula STR1 wherein R is alkyl, alkenyl, alkynyl or alkoxyalkyl, as well as their salts, are described. The compounds of formula I have valuable, long-lasting vasodilating and/or blood pressure-lowering properties and are useful for the treatment of vascular-conditioned hypertensions or as vasodilators in peripheral blood supply disorders. The compounds are prepared, inter alia, by carbamoylating the corresponding derivative containing a free amino group and optional salt formation.
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(2008/06/13)