- Preparation method of PF-06651600 intermediate
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The invention relates to a preparation method of a PF-06651600 intermediate, and belongs to the field of medicinal chemistry. According to the method, 3-amino-6-methylpyridine can be used as a raw material, and a target compound is obtained through amino protection, quaternization, reduction, ketone formation, imine formation, reduction and amino protection. The method has the advantages of mild conditions, readily available reagents, high product purity, high yield and safe operation, and can be used for industrial production.
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Paragraph 0062-0064
(2021/02/10)
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