- COMPOUND RETAINED IN TUMOR
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A novel compound which specifically resides in a tumor, a method for allowing it to reside in a tumor, and a method for detecting, diagnosing, and treating tumor with use thereof are provided. The present invention relates to a compound represented by chemical formula (I) wherein R is an anionic group binding to hydrogen, R1 is OH, OCOH, OCO(CH2)hCH3, or an acting group, h being an integer of 0 or more, R2 is H, OH, OCOH, OCO(CH2)iCH3, or an acting group, i being an integer of 0 or more, R3 is OH, SO3H, or an acting group, R4 is OH, SO3H, or an acting group, and R5 is OH, SO3H, or an acting group, at least one of R1, R2, R3, R4, and R5 containing an acting group, or pharmaceutically acceptable salts thereof.
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- SYNTHESIS OF SULFATED GLYCOHEXAOSE OF LINKAGE REGION OF CHONDROITIN 4-SULFATE: β-D-GlcA-(1->3)((SO3Na->4))-β-D-GalNAc-(1->4)-β-D-GlcA-(1->3)-β-D-Gal-(1->3)-β-D-Gal-(1->4)-D-Xyl
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Stereocontrolled synthesis of glycohexaoses 3 and 4 which corresponds to the linkage region of chondroitin 4-sulfate to a core protein was achieved for the first time by employing glycotriosyl donor 5 and glycotriosyl acceptor 6.
- Goto, Fumitaka,Ogawa, Tomoya
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p. 6841 - 6844
(2007/10/02)
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- Synthetic Studies on Rhynchosporoside and Related Substances
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The stereoselective synthesis of the 1-O-α-D-glucopyranosides and 1-O-α-D-cellobiosides of 3-deoxy-2(R)- and 2(S)-glycerols to determine the complete stereochemistry of rhynchosporoside, which is a host selective phytotoxin from Rhynchosporium secalis, is
- Sugawara, Fumio,Nakayama, Haruhiko,Strobel, Gary A.,Ogawa, Tomoya
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p. 2251 - 2260
(2007/10/02)
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