- Diphosphine compounds: Part I. Novel biologically active 1,1′bis-and/or 1,2-cis-(diphenylphosphino-)ethene and their complexes [M(CO)n{Ph2P(CHn)nPPh2}] & [Cu(Cl)2{Ph2P(CHn)nPPh 2}], (M = W, Mo, Crn = 1,2...n)
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Interaction of [Ph2PC(=CH2)PPh2] (A) 1-3 and/or [Ph2P (CH=CH) PPh2](B) ligands in different molar ratio with hexacarbonyl metals M(CO)6 gives [M(CO)nPh2PC(=CH2)PPh2] and/or [M(CO)nPh2P (CH=CH)PPh2 where M=Cr, Mo or W, n = 2 and/or 4]. The carbon diphosphine complexes of type (A) which form four heteromemebered rings and/or type (B) form five heteromembered rings which reacts (addition reaction) with some different amines (methyl arnine, dimethyl anime), phenyl hydrazine and/or some of amino acids (glycine, alanine, aspartic acid, serene). The structures of A and/or B complexes and their amino derivatives have been characterized by using elemental analysis, IR spectra, 1HNMR,1H-{31P}-NMR, and mass spectra. Ligands and their complexes were screened in vitro to investigate the biological activities (antibacterial and antifungi). Interestingly, complexes are having strong and remarkable activities increases than the free ligands.
- Awad, Ibrahim M. A.,Hassan, Fatma S. M.,Mohamed, Adila E.,Al-Hossainy, Ahmed F.
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- Nickel-catalyzed cross-coupling of diphenylphosphine with vinyl bromides and chlorides as a route to diphenylvinylphosphines
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An efficient nickel-catalyzed reaction for the phosphination of vinyl bromides and chlorides was developed. The procedure uses a combination of up to 1 mol% of nickel acetylacetonate, triethylamine and dimethylformamide as a solvent. The double bond geometry of the vinyl halides was retained under the reaction conditions.
- Shulyupin, Mstilsav O.,Chirkov, Evgeniy A.,Kazankova, Marina A.,Beletskaya, Irina P.
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p. 658 - 660
(2007/10/03)
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- Reactivity of carbanions stabilized by two alpha phosphorus groups
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The stabilized anion {[Ph2P(S)]2CH}- with lithium as counter cation 1a reacts with formaldehyde or benzaldehyde to give vinylidene phosphine sulfides [Ph2P(S)]2C=CHR, where R is H or Ph, respectively
- Goli,Grim
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p. 3631 - 3634
(2007/10/02)
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- Structure Comparison of H2C=C(PPh2)2 and Ph3P=C(PPh2)2. A Contribution to the P=C Double Bond Problem in Ylides
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Through a structure analysis of H2C=C(PPh2)2 (1) the conformation-determining effect of the C=C double bond could be compared with that of the P=C double bond in the ylide Ph3P=C(PPh2)2 (A).Single crystal X-ray diffraction of 1 showed that indeed analogous conformations of the Ph2P groups relative to the basic plane of the molecule are present in the solid.However, the directing influence is much weaker in 1 than in A, and in solution even at -75 deg C no non-equivalence of the P-atoms is detectable by 31P-NMR spectroscopy.The restricted rotation previously found for A is therefore attributed to the gauche effect of the lone pairs of electrons at PIII and the ylidic C atom.According to bond distances, no ?-interactions C=P can be diagnosed in 1, while significant contributions of this type seem to be valid for A.
- Schmidbaur, Hubert,Herr, Rudolf,Riede, Juergen
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p. 2322 - 2327
(2007/10/02)
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