cas 848-75-9, LORMETAZEPAM | Articles data

Articles about 848-75-9Total 2 be found

Crystal form of lormetazepam and preparation method thereof
The invention relates to lormetazepam, in particular to a crystal form of lormetazepam and a preparation method thereof. The reflecting angle 2theta in the X-ray powder diffraction pattern of the crystal form of lormetazepam has characteristic peaks at 12.20 degrees, 14.69 degrees, 14.77 degrees, 18.43 degrees, 18.55 degrees, 20.85 degrees, 21.19 degrees, 24.43 degrees and 28.32 degrees. The preparation method comprises the steps of: adding a solvent into a lormetazepam crude product, heating up till backflow, after full dissolution of the crude product, continuing heat-insulated backflow, filtering after backflow is finished, cooling and carrying out heat-insulated crystallization on the filtrate, then filtering, and drying the filter cake to a constant weight to obtain the crystal form of lormetazepam. The preparation method disclosed by the invention is simple in operation and easy in realization.
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Paragraph 0024; 0025; 0026; 0027

(2016/10/24)

Benzodiazepine derivatives
The present invention is directed to novel benzodiazepine derivatives which are synthesized for the covalent attachment to antigens (proteins or polypeptides) for the preparation of antibodies or receptors to the benzodiazepine metabolites. The resulting novel antigens may be used for the production of antibodies or receptors using standard methods. Once generated, the antibodies or receptors and the novel derivatives which are covalently attached to proteins, polypeptides or labels may be used in the immunoassay process.
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(2008/06/13)