- Modifications on the Heterocyclic Base of Acyclovir: Syntheses and Antiviral Properties
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A griup of compounds were prepared in which variations of the ring portion of the acyclovir (ACV) structure were made.These modifications included monocyclic (isocytosine, triazole, imidazole), bicyclic (8-azapurine, pyrrolo pyrimidine, pyrazolo3,
- Beauchamp, Lilia M.,Dolmatch, Bart L.,Schaeffer, Howard J.,Collins, Peter,Bauer, D. J.,et al.
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p. 982 - 987
(2007/10/02)
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- Synthesis of Acyclo-7-deazaguanosine by Regiospecific Phase-Transfer Alkylation of 2-Amino-4-methoxy-7H-pyrrolopyrimidine
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Acyclo-7-deazaguanosine (2), a structural analogue of the antiviral highly active acycloguanosine (1), has been synthesized.Regiospecificity of the electrophilic attack was shown by phase-transfer methylation of 2-amino-4-methoxy-7H-pyrrolopyrimidi
- Seela, Frank,Kehne, Andreas,Winkeler, Heinz-Dieter
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p. 137 - 146
(2007/10/02)
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