The invention described herein relates to certain bicyclic heteroaromatic N-substituted glycine derivatives of formula (I) which are antagonists of HIF prolyl hydroxylases and are useful for treating diseases benefiting from the inhibition of this enzyme, anemia being one example.
-
Page/Page column 7-8
(2008/06/13)
Inhibitors of HCV NS5B polymerase: Synthesis and structure-activity relationships of N-1-heteroalkyl-4-hydroxyquinolon-3-yl-benzothiadiazines
N-1-Alkylamino and N-1-alkyloxy-4-hydroxyquinolon-3-yl benzothiadiazines were synthesized and evaluated as inhibitors of genotype 1 HCV polymerase. The N-1-alkyloxy derivatives were not potent inhibitors, however N-1-alkylamino derivatives displayed compa
Pratt, John K.,Donner, Pamela,McDaniel, Keith F.,Maring, Clarence J.,Kati, Warren M.,Mo, Hongmei,Middleton, Tim,Liu, Yaya,Ng, Teresa,Xie, Qinghua,Zhang, Rong,Montgomery, Debra,Molla, Akhteruzzaman,Kempf, Dale J.,Kohlbrenner, William
p. 1577 - 1582
(2007/10/03)
More Articles about upstream products of 850814-34-5