Transition-Metal Catalysis of Triene 6π Electrocyclization: The π-Complexation Strategy Realized
Triene 6π electrocyclization, wherein a conjugated triene undergoes a concerted stereospecific cycloisomerization to a cyclohexadiene, is a reaction of great historical and practical significance. In order to circumvent limitations imposed by the normally
Baldridge, Kim K.,Chen, Jiyue,Li, Yifan,O'Connor, Joseph M.,Qin, Pengjin,Rheingold, Arnold L.,Tufekci, Burak,Wang, Li-An
p. 17958 - 17965
(2020/08/19)
Ruthenium-catalyzed regioselective 1,3-methylene transfer by cleavage of two adjacent σ-carbon-carbon bonds: An easy and selective synthesis of highly subsituted benzenes
We report a new ruthenium-catalyzed 6-endo-dig cyclization of 6,6-cycloalkylidenyl-3,5-dien-1-ynes, which produces highly substituted benzenes with considerable structural reorganization. In this process, we observe a regioselective 1,3-methylene migratio