Novel phenylamino acetamide derivatives as potent and selective κ opioid receptor agonists
A novel series of phenylamino acetamide derivatives was synthesized. These amides were shown to be potent and selective κ opioid receptor agonists.
Chu, Guo-Hua,Gu, Minghua,Cassel, Joel A.,Belanger, Serge,Stabley, Gabriel. J.,DeHaven, Robert N.,Conway-James, Nathalie,Koblish, Mike,Little, Patrick J.,DeHaven-Hudkins, Diane L.,Dolle, Roland E.
p. 645 - 648
(2007/10/03)
Amide derivatives and methods of their use
Amide derivatives of the general formulae Ia and Ib: are disclosed. Pharmaceutical compositions containing these compounds, and methods for their use, inter alia, for treating and/or preventing gastrointestinal disorders, pain, and pruritus are also disclosed.
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Page/Page column 31
(2008/06/13)
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