Total synthesis of nigellicine and nigeglanine hydrobromide
(Chemical Equation Presented) The first syntheses of the pyridazinoindazolium alkaloids nigellicine and nigeglanine hydrobromide via a common intermediate are described. Ortho-lithiation/acylation and the direct amination of an isatin ring system are the
Elliott, Eric L.,Bushell, Simon M.,Cavero, Marta,Tolan, Brian,Kelly, T. Ross