Facile preparation of difluoromethyl- and monofluoromethyl-containing amides via Ritter reaction
Both secondary and tertiary difluoromethylated carbinols were found to readily react with acetonitrile under the catalysis of concentrated sulfuric acid to give the corresponding difluoromethylated acetamides in good yields, which is remarkably more effic
Convenient synthesis of difluoromethyl alcohols from both enolizable and non-enolizable carbonyl compounds with difluoromethyl phenyl sulfone
A general and efficient nucleophilic difluoromethylation of carbonyl compounds (both enolizable and non-enolizable aldehydes and ketones) has been achieved by using a nucleophilic (phenylsulfonyl)difluoromethylation-reductive desul fonylation strategy. Di
Prakash, G.K.Surya,Hu, Jinbo,Wang, Ying,Olah, George A.
p. 2218 - 2223
(2007/10/03)
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