- A 4 - phenyl coumarin compound of preparation method
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The invention belongs to the technical field of organic compound synthesis and discloses a preparation method of a 4-phenylcoumarin compound. The preparation method solves the problem that the existing coumarin compound synthesis method produces single co
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Paragraph 0071-0074
(2017/08/31)
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- Copper/Selectfluor-System-Catalyzed Dehydration-Oxidation of Tertiary Cycloalcohols: Access to β-Substituted Cyclohex-2-enones, 4-Arylcoumarins, and Biaryls
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A route to β-substituted cyclohex-2-enones, 4-arylcoumarins, and biaryls has been developed. This approach involves a one-pot Cu0/Selectfluor-catalyzed dehydration-oxidation of tertiary cycloalcohols. Thus, by using 2 equiv. of Selectfluor at 25 C, the dehydration-oxidation of tertiary cyclohexanols and oxabenzocyclohexanols gave β-substituted cyclohex-2-enones and 4-arylcoumarins, respectively; whereas the dehydration-oxidation of tertiary cyclohexanols gave biaryls as the final products by using 2.5 equiv. of Selectfluor at 80 C. A route to β-substituted cyclohex-2-enones, 4-arylcoumarins, and biaryls has been developed. This approach involves a one-pot Cu0/Selectfluor-catalyzed dehydration-oxidation of tertiary cycloalcohols.
- Ren, Shaobo,Zhang, Jian,Zhang, Jiahui,Wang, Heng,Zhang, Wei,Liu, Yunkui,Liu, Miaochang
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supporting information
p. 5381 - 5388
(2015/08/24)
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- Palladium-catalyzed oxidative heck coupling reaction for direct synthesis of 4-arylcoumarins using coumarins and arylboronic acids
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An efficient protocol for the direct synthesis of 4-arylcoumarins via palladium-catalyzed oxidative Heck coupling reaction of coumarins and arylboronic acids was developed. 4-Arylcoumarins were obtained in moderate to excellent yields, and the reaction also showed tolerance toward functional groups such as hydro, methoxy, diethylamino, nitro, and chloro groups.
- Li, Yaming,Qi, Zisong,Wang, Huifeng,Fu, Xinmei,Duan, Chunying
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supporting information; experimental part
p. 2053 - 2057
(2012/04/04)
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- Synthesis of coumarins in a molten n-Bu4NOAc/n-Bu4NBr mixture through a domino heck reaction/cyclization process
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4-Arylcoumarins can be prepared in good to high yields by reacting readily available methyl or butyl 3-(ohydroxyaryl)acrylates with aryl iodides and bromides in an n-Bu4NOAc/n-Bu4NBr mixture at 100°C in the presence of Pd(OAc)2.
- Battistuzzi, Gianfranco,Cacchi, Sandro,De Salve, Ilse,Fabrizi, Giancarlo,Parisi, Luca M.
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p. 308 - 312
(2007/10/03)
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