- (5R, 8S, 10R)-6-ALKYL-8-ERGOLINECARBOXYLIC ACIDS AND SOME OF THEIR DERIVATIVES
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(5R, 8S, 10R)-6-methyl-8-methoxycarbonylergoline (VIIb) was converted via Ib and IIb into its 6-analogues IIIb-VIb, which, in turn, were converted into acids IIIa-VIa and hydrazides IIIc-VIc.Some of the esters prepared, mainly IVb, had inhibitory effects on the secretion of prolactin in rats.
- Cerny, Antonin,Zikan, Viktor,Vlckova, Drahuse,Benes, Jan,Holubek, Jiri,et al.
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p. 1483 - 1489
(2007/10/02)
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