Probing the cannabinoid CB1/CB2 receptor subtype selectivity limits of 1,2-diarylimidazole-4-carboxamides by fine-tuning their 5-substitution pattern
The cannabinoid CB1/CB2 receptor subtype selectivity in the 1,2-diarylimidazole-4-carboxamide series was boosted by fine-tuning its 5-substitution pattern. The presence of the 5-methylsulfonyl group in 11 led to a greater than ~840-f
Lange, Jos H.M.,van der Neut, Martina A.W.,Borst, Alice J.M.,Yildirim, Mahmut,van Stuivenberg, Herman H.,van Vliet, Bernard J.,Kruse, Chris G.
scheme or table
p. 2770 - 2775
(2010/07/08)
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