Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors
We describe the structure-based design and synthesis of highly potent, orally bioavailable tissue factor/factor VIIa inhibitors which interfere with the coagulation cascade by selective inhibition of the extrinsic pathway.
Zbinden, Katrin Groebke,Obst-Sander, Ulrike,Hilpert, Kurt,Kuehne, Holger,Banner, David W.,Boehm, Hans-Joachim,Stahl, Martin,Ackermann, Jean,Alig, Leo,Weber, Lutz,Wessel, Hans Peter,Riederer, Markus A.,Tschopp, Thomas B.,Lave, Thierry
p. 5344 - 5352
(2007/10/03)
More Articles about upstream products of 871345-44-7