- An efficient and odorless synthesis of thioethers using 2-[Bis(alkylthio)methylene]-3-oxo-N-o-tolylbutanamides as thiol equivalents
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Using 2-[bis(alkylthio)methylene]-3-oxo-N-o-tolylbutanamides 1 as odorless thiol equivalents, an efficient and odorless synthesis of thioethers has been developed. Promoted by NaOH in EtOH, the cleavage of 1 commences to generate thiolate anions, and the generated thiolate anions then react with halides to give various thioethers in good yield. It is noteworthy that only a very faint odor of thiols can be perceived during both the reaction and the workup. Using 2-[bis(alkylthio)methylene]-3-oxo-N-o-tolylbutanamides as odorless thiol equivalents, an efficient and odorless synthesis of thioethers has been developed. Promoted by NaOH in EtOH, the cleavage of 2-[bis(alkylthio)methylene] -3-oxo-N-o-tolylbutanamides commences to generate thiolate anions, and the generated thiolate anions then react with halides to give various thioethers in good yield. Copyright
- Yu, Haifeng
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p. 367 - 371
(2012/04/23)
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- Thia-Michael addition reactions using 2-[bis(alkylthio)methylene]-3-oxo-N- o-tolylbutanamides as odorless and efficient thiol equivalents
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A series of 2-[bis(alkylthio)methylene]-3-oxo-N-o-tolylbutanamides 1 have been investigated as nonthiolic and odorless thiol equivalents in thia-Michael addition reactions. The cleavage of compounds 1 is initiated by NaOH in EtOH; the in situ generated th
- Dong, Dewen,Yu, Haifeng,Ouyang, Yan,Liu, Qun,Bi, Xihe,Lu, Yumei
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p. 283 - 287
(2007/10/03)
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- A clean, facile and practical synthesis of α-oxoketene S,S-acetals in water
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A clean, facile and practical synthesis of α-oxoketene S,S-acetals in water has been developed. Catalyzed by tetrabutylammonium bromide (TBAB) at room temperature in water, a range of β-dicarbonyl compounds have been converted to the corresponding α-oxoke
- Ouyang, Yan,Dong, Dewen,Yu, Haifeng,Liang, Yongjiu,Liu, Qun
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p. 206 - 210
(2007/10/03)
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