REGIO-AND STEREOSELECTIVE PALLADIUM CATALYZED AMINATION OF ALLYLIC SUBSTRATES. SYNTHESIS OF E-4-AMINO-2-ALKEN-1-OL DERIVATIVES
Under mild conditions 4, 5 and 6 react with primary and secondary amines in the presence of palladium phosphine complexes as catalysts to give 4-amino-2-alken-1-ols with (E) stereochemistry.