- Synthesis of 3-Acyl-Isoxazoles via Radical 5-endo trig Cyclization of β,γ-Unsaturated Ketones with NaNO2
-
Here we report a facile cyclization reaction of β,γ-unsaturated ketones with NaNO2 under mild conditions to construct 3-acyl-isoxazoles. This transformation is realized via nitrosation of the activated methylene, radical 5-endo trig cyclization
- Chen, Dengfeng,Huang, Shenlin,Jiang, Ping,Wang, Yaming,Zheng, Yu
-
supporting information
(2022/02/07)
-
- Intramolecular Cyclization of Vinyldiazoacetates as a Versatile Route to Substituted Pyrazoles
-
Vinyldiazo compounds undergo a thermal electrocyclization to form pyrazoles in yields of up to 95percent. The reactions are operationally simple, use readily available starting materials, require no intervention of a catalyst, and enable the synthesis of mono-, di- A nd tri-substituted pyrazoles. With the ability to produce highly substituted pyrazoles and the flexibility in installing various types of substituents, this method constitutes a new entry to this valuable heterocyclic scaffold and may be of interest to all branches of the chemical industry.
- Drikermann, Denis,G?rls, Helmar,Kerndl, Valerie,Vilotijevic, Ivan
-
p. 1158 - 1162
(2020/07/20)
-
- In/InCl3-mediated cross-coupling reactions of methyl vinyl ketone with benzaldehyde in aqueous media
-
(matrix presented) Various β,γ-unsaturated ketones were successfully prepared by cross-coupling reactions of methyl vinyl ketone (MVK) with benzaldehydes mediated by In/InCl3 in aqueous media.
- Kang, Soyeon,Jang, Taeg-Su,Keum, Gyochang,Kang, Soon Bang,Han, So-Yeop,Kim, Youseung
-
p. 3615 - 3617
(2007/10/03)
-
- Phase Transfer Generation of Acyltetracarbonyliron Anions: their Role in the Phase Transfer Carbonylation of Reactive Halides to give Carboxylic Acids and Symmetrical and Unsymmetrical Ketones
-
Acyltetracarbonyliron anions RCOFe(CO)4(1-) (3) are readily synthesised under mild phase transfer (PT) conditions from pentacarbonyliron and reactive organic halides; the in situ generated anions (3) (R = ArCH2) are the true catalysts in the PT carbonylation of benzyl halides to give ketones or carboxylic acids.
- Laurent, Pascale,Tanguy, Guy,Abbayes, Herve des
-
p. 1754 - 1756
(2007/10/02)
-
- REDUCTIVE CONVERSION OF NITRO ALKENES TO KETONES AND/OR OXIMES IN AN AQUEOUS HClO4-CH2Cl2-DIOXANE-(Pb) SYSTEM
-
Electrochemical and chemical reduction of nitro alkenes in an aqueous HClO4-CH2Cl2-dioxane-(Pb) system afforded ketones and oximes in good yields, each of which can be obtained selectively by treating with either aqueous formaldehyde or hydroxylamine as a proper workup process, respectively.
- Torii, Sigeru,Tanaka, Hideo,Katoh, Tetsuo
-
p. 607 - 610
(2007/10/02)
-
- ADDITION DE L'ACETONE A DES ALCYNES VRAIS FONCTIONNELS OU NON
-
Acetonyl radicals created by action of di-t-butylperoxide on acetone (molar ratios acetone/acetylenic compound/DTBP = 20/1/0.2 ; 150 deg C ; 3h) add to acetylenic compounds and lead to the formation of 1/1 adducts in low to moderate yields. 2/1 adducts ar
- Gardrat, C.,Montaudon, E.,Lalande, R.
-
p. 1039 - 1042
(2007/10/02)
-