cas 87885-45-8, 2-CHLORO-5-NITROPYRAZINE | Articles data

A series of eight novel nitropyrazines has been prepared by oxidation of sulfoximine intermediates. The partition coefficient, one-electron reduction potential, sensitizer enhancement ratio, and chronic and acute aerobic cytotoxicity have been measured for each. Two representatives of this series were tested in the Ames test and were not found to be mutagenic.

Treatment of 2-chloro-3-nitropyrazine and 2-chloro-5-nitropyrazine with 3-amino-1,2-propranediol affords products derived from displacement of chloride, while similar reaction of methyl 3-nitropyrazinoate and 2-chloro-3-nitroquinoxaline gives clean nitro group replacement. Analogous reaction of methyl 6-chloro-3-nitropyrazinoate affords a mixture containing products derived from competitive displacement of chloride and nitrite.

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Chemical Properties

Melting Point: 88-90 °C

Boiling Point: 279.2 °C at 760 mmHg

Flash Point:122.7 °C

Density: 1.6 g/cm³

Storage Temp.:2-8°C

PKA: -5.91±0.10(Predicted)

PSA: 71.60000

LogP: 1.56140

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87885-45-8

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More Articles about upstream products of 87885-45-8

Chemical Properties

Melting Point: 88-90 °C

Boiling Point: 279.2 °C at 760 mmHg

Flash Point:122.7 °C

Density: 1.6 g/cm3

Storage Temp.:2-8°C

PKA: -5.91±0.10(Predicted)

PSA: 71.60000

LogP: 1.56140

Global suppliers and manufacturers of 87885-45-8total 22 suppliers on LookChem

Density: 1.6 g/cm³