- Synthesis method of o-tert-butyl cyclohexyl acetate essence
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The invention discloses a synthesis method of o-tert-butyl cyclohexyl acetate essence, which includes the following steps: a) successively adding petroleum ether and phenol to a three-neck glass flask, and adding TiO2-supported phosphotungstic acid catalyst, dropwise adding tert-butyl alcohol at 10 - -15 DEG C, and layering a reaction liquid mixture, generated in the glass flask, of o-tert-butyl phenol and p-tert-butyl phenol; b) washing an oil layer successively with alkali and water, and performing a hydrogenation reaction under a Pd/C catalyst, collecting o-tert-butyl cyclohexanol, adding acetic anhydride and p-toluenesulfonic acid, recovering the acetic acid, and alkali-washing, water-washing and evaporating the oil layer to prepare the o-tert-butyl cyclohexyl acetate essence. The method employs easy-to-obtained raw materials and is high in yield, wherein final product content can reach more than 98.5% and content of cis-isomers in the product can reach more than 85%. The ssence has a pure and mellow fragrance and satisfies the demand of essence and perfumes in flavor blending.
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Paragraph 0015; 0016; 0017
(2018/04/26)
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- Transesterification/Acylation of Secondary Alcohols Mediated by N-Heterocyclic Carbene Catalysts
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N-Heterocyclic carbenes (NHC) are efficient catalysts for transesterification/acylation reactions involving secondary alcohols. The catalytic transformations are carried out employing low catalyst loadings in convenient reaction times at room temperature.
- Singh, Rohit,Kissling, Rebecca M.,Letellier, Marie-Anne,Nolan, Steven P.
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p. 209 - 212
(2007/10/03)
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