- Biomimetic aerobic oxidation of amino alcohols to lactams
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The right path: N-Protected amino alcohols undergo aerobic and biomimetic oxidation to the corresponding lactams in the presence of a ruthenium catalyst and a combination of electron-transfer mediators under air (see scheme). The reaction was used for the synthesis of five-, six-, and seven-, membered lactams and showed good tolerance to a number of N-protecting groups. Copyright
- Babu, Beneesh P.,Endo, Yoshinori,Baeckvall, Jan-E.
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p. 11524 - 11527,4
(2012/12/11)
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- Efficient synthesis of functionalized benzazepine derivatives utilizing intramolecular mitsunobu reaction
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The 5-hydroxy-2,3,4,5-tetrahydro-1H-benzazepine derivative (2), which is a typical metabolite of mozavaptan (1) having the 2,3,4,5-tetrahydro-1H-benzazepine skeleton, was synthesized by utilizing the intramolecular Mitsunobu reaction of the corresponding
- Ohtani, Tadaaki,Kawano, Yoshikazu,Kitano, Kazuyoshi,Matsubara, Jun,Komatsu, Makoto,Uchida, Minoru,Tabusa, Fujio,Nagao, Yoshimitsu
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p. 481 - 502
(2007/10/03)
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