- Photoinduced Trifluoromethylation of Arenes and Heteroarenes Catalyzed by High-Valent Nickel Complexes
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We describe a series of air-stable NiIII complexes supported by a simple, robust naphthyridine-based ligand. Access to the high-valent oxidation state is enabled by the CF3 ligands on the nickel, while the naphthyridine exhibits either a monodentate or bidentate coordination mode that depends on the oxidation state and sterics, and enables facile aerobic oxidation of NiII to NiIII. These NiIII complexes act as efficient catalysts for photoinduced C(sp2)?H bond trifluoromethylation reactions of (hetero)arenes using versatile synthetic protocols. This blue LED light-mediated catalytic protocol proceeds via a radical pathway and demonstrates potential in the late-stage functionalization of drug analogs.
- Deolka, Shubham,Govindarajan, Ramadoss,Khaskin, Eugene,Fayzullin, Robert R.,Roy, Michael C.,Khusnutdinova, Julia R.
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supporting information
p. 24620 - 24629
(2021/10/08)
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- An enantioselective synthesis of (R)- and (S)-3-amino-7-methyl-3,4-dihydro- 1H-[1,8]naphthyridin-2-one
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An enantioselective synthesis of (R)- and (S)-3-amino-7-methyl-3,4-dihydro- 1H-[1,8]naphthyridin-2-one via an asymmetric reduction and spontaneous cyclisation is reported.
- Badland, Matthew,Carroll, Robert,Chadwick, Claire,Cheung, Joe Waichiu,Fussell, Steve,Laity, Daniel,Peach, Philip,Shaw, David
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experimental part
p. 1328 - 1331
(2011/11/28)
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- HERBICIDAL COMPOUNDS
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The present invention relates to novel herbicidal oxopyridine and thionopyridine derivatives of Formula (I), or an agronomically acceptable salt of said compound wherein R1, R5, R6, R7, X1, X2/s
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Page/Page column 35
(2010/11/03)
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- HERBICIDAL COUMPOUNDS
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The present invention relates to novel herbicidal [l,8]-naphthyridines of Formula (Ia) or (Ib), or an agronomically acceptable salt of said compound wherein R2, R3, R4, R5,R6,R7, R8, n, m, X and Q are as defined herein. The invention further relates to processes and intermediates for the preparation of the [l,8]-naphthyridines, to compositions which comprise the herbicidal compounds, and to their use for controlling weeds, in particular in crops of useful plants.
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Page/Page column 105
(2009/10/22)
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