cas 885278-66-0, 2-(3-AMINO-PHENYL)-THIAZOLE-4-CARBOXYLIC ACID ETHYL ESTER | Articles data ｜lookchem

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885278-66-0

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Synthesis and evaluation of potent and selective β3 adrenergic receptor agonists containing heterobiaryl carboxylic acids
The design, synthesis, and SAR of a novel series of heterobiaryl phenethanolamine β3 adrenergic receptor agonists are described. The furan analogue 49 was shown to elicit a significant dose-dependent lowering of plasma glucose in a rodent model
Shearer, Barry G.,Chao, Esther Y.,Uehling, David E.,Deaton, David N.,Cowan, Conrad,Sherman, Bryan W.,Milliken, Tula,Faison, Walter,Brown, Kathleen,Adkison, Kimberly K.,Lee, Frank
p. 4670 - 4677
(2008/02/12)

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950603-74-4
C₃₄H₄₈ClN₃O₅SSi

Chemical Properties

Boiling Point: 440.8±51.0 °C(Predicted)
Density: 1.279±0.06 g/cm3(Predicted)
PKA: 3.49±0.10(Predicted)
PSA: 93.45000
LogP: 3.15020

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