- Visible-light-induced triple catalysis for a ring-opening cyanation of cyclopropyl ketones
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An unprecedented triple catalytic, general ring-opening cyanation reaction of cyclopropyl ketones for the construction of γ-cyanoketones is described. The key is to merge photoredox catalysis with Lewis acid catalysis and copper catalysis to enable the selective cleavage of the carbon-carbon bonds and the selective coupling of the generated radical and cyanide anion.
- Liu, Jing,Liu, Xiao-Peng,Wu, Hong,Wei, Yi,Lu, Fu-Dong,Guo, Kai-Rui,Cheng, Ying,Xiao, Wen-Jing
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p. 11508 - 11511
(2020/10/12)
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- Activation of nitriles by metal ligand cooperation. reversible formation of ketimido- and enamido-rhenium PNP pincer complexes and relevance to catalytic design
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The dearomatized complex cis-[Re(PNPtBu*)(CO)2] (4) undergoes cooperative activation of Ci - N triple bonds of nitriles via [1,3]-addition. Reversible C-C and Re-N bond formation in 4 was investigated in a combined experimental and c
- Vogt, Matthias,Nerush, Alexander,Iron, Mark A.,Leitus, Gregory,Diskin-Posner, Yael,Shimon, Linda J. W.,Ben-David, Yehoshoa,Milstein, David
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supporting information
p. 17004 - 17018
(2013/12/04)
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- Cesium carbonate supported on alumina for the michael addition of diethyl malonate to methyl acrylates
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The cesium salts supported on γ-Al2O3 were highly active catalysts for the Michael addition of diethyl malonate (1) to methyl acrylate (2) in toluene as solvent. The use of a limited amount of 2 gave diethyl [2-(methoxycarbonyl)ethyl
- Hida, Tetsunari,Komura, Kenichi,Sugi, Yoshihiro
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experimental part
p. 960 - 967
(2011/10/17)
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- Heterocyclic-substituted alkylamide acat inhibitors
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Pharmaceutically useful compounds having ACAT inhibitory activity of the formula wherein n is 0, 1, or 2, for X other than tetrazole and n = 2 then R2 = R3 = H; R1 is phenyl, substituted phenyl, naphthyl, substituted naphthyl, a heteroaromatic group or a hydrocarbon group having from one to 18 carbon atoms; R2 and R3 are hydrogen, halo, hydroxy, alkyl, alkenyl, cycloalkyl, phenyl, substituted phenyl, a heteroaryl, or form a spiroalkyl group; x is a 5-membered heteromonocyclic group containing at least one to four heteroatoms selected from the group consisting of isothiazole, oxazole, thiazole, imidazole, furan, thiophene, pyrrole, tetrazole, 1,2,3-triazole, 1,2,4-oxadiazole, 1,3,4-oxadiazole, 1,3,4-thiadiazole, 1,2,4-triazole, and 1,2,4-oxadiazole said heteromonocyclic group being unsubstituted or substituted at any available position along the ring,
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- Rhodium-Catalyzed Michael Additions of Activated Nitriles to α,β - Unsaturated Esters
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The Michael additions of activated nitriles to methyl acrylate (MA) and methyl vinyl ketone (MVK) proceeds with fair-to-high yields (46-92percent) in the presence of catalytic amount of HRh(CO)(PPh3)3 1 under mild reaction conditions.Key Words: Michael ad
- Paganelli, Stefano,Schionato, Alberto,Botteghi, Carlo
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p. 2807 - 2810
(2007/10/02)
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