2-PHENYLIMIDAZO[4,5-B]PYRIDIN-7-AMINE DERIVATES USEFUL AS INHIBITORS OF MAMMALIAN TYROSINE KINASE ROR1 ACTIVITY
Compound of formula (I′) or (I′′) or a pharmaceutically acceptable salt thereof. The compound is an inhibitor of mammalian kinase enzyme activity, including ROR1 tyrosine kinase activity and may be used in the treatment of disorders associated with such activity.
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Page/Page column 89-90; 91-92; 93
(2018/03/26)
Pyrrolidinone derivatives
Since a compound represented by general formula (1), its pharmaceutically acceptable salt and a hydrate of the pharmaceutically acceptable salt have high antipsychotic activity, they may be used as an active ingredient for preparation of an antipsychotic. STR1 Also provided are an optical resolution method of the above compound and an intermediate for preparation of the compound.
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(2008/06/13)
Potential hypnotics and anxiolytics in the 4H-s-triazolo[4,3-a]-1,4-benzodiazepine series: 8-chloro-6-(2-chlorophenyl)-1-[4-(2-methoxyethyl)-piperazino]-4H-s-triazolo[ 4,3-a]-1,4-benzodiazepine and some related compounds
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Polivka,Ryska,Holubek,et al.
p. 2395 - 2410
(2007/10/02)
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