- Polyenic acids. I. Antifungal and bacteriostatic activities of hexa-2,4 dienoic acid derivatives
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Synthesis of esters and amides of 2,4-(2 E, 4 E) hexadienoic acid are reported. The authors have tried to modulate the polarity of these compounds by introducing sequences with hydroxyl, amino groups, ether, thioether functions and halogen atoms or heterocycles. A gain in bacteriostatic activity, compared with sorbic acid has been stated in some cases, it is accompanied by either a breakdown (compounds 3, 38, 51, and 54) or a maintenance of fungistatic activity (compounds 5, 10 and 17).
- Le Baut,Sparfel,Clairc,et al.
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p. 441 - 445
(2007/10/02)
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