Tetrahydronaphthalene and indane compounds useful as anti-tumor agents
This invention is directed to tetrahydronaphthalene and indane compounds and processes thereto. These compounds are useful as tumor inhibiting agents, in the treatment of neoplasms and dermatological conditions.
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(2008/06/13)
Sulfur-containing arotinoids, a new class of retinoids
The synthesis and biological activity of a new class of retinoids with a sulfur containing end group instead of a carboxylic acid, is described. The most active compound, the ethyl sulfone 14 has a 5 times better therapeutic index than retinoic acid. Whil
Klaus,Bollag,Huber,Kung
p. 425 - 429
(2007/10/02)
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