- Synthesis of haptens for the development of a solid-phase immobilized epitope-immunoassay (SPIE-IA) of AZT-TP
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The synthesis of the reduced form of AZT-triphosphate, 3'-amino-3'- deoxythymidine-5'-triphosphate, and of its stable analog, 3'-amino-3'- deoxythymidine-5'-(α,β:β,γ-bis-methylene)triphosphate, is described. AMT- TP and AMT-PCPCP were prepared to develop
- Lebeau, Luc,Brossette, Thierry,Goujon, Laure,Creminon, Christophe,Grassi, Jacques,Mioskowski, Charles
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Read Online
- Nucleic acid labeling compounds
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Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. Methods for making such heterocyclic compounds are also disclosed. The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.
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- Nucleic acid labeling compounds
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Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. The heterocyclic derivative containing compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofuranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.
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- Nucleic acid labeling compounds
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Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. The heterocyclic derivative containing compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofuranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.
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- Nucleic acid labeling compounds
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Nucleic acid labeling compounds containing heterocyclic derivatives are disclosed. The heterocyclic derivative containing compounds are synthesized by condensing a heterocyclic derivative with a cyclic group (e.g. a ribofuranose derivative). The labeling compounds are suitable for enzymatic attachment to a nucleic acid, either terminally or internally, to provide a mechanism of nucleic acid detection.
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- A facile solid phase synthesis of 2′- and 3′-aminonucleoside triphosphates
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A convenient and time-saving solid phase synthesis of different 2′- and 3′-amino-functionalized nucleoside-5′-triphosphates using polymer bounded triphenylphosphine is described.
- Schoetzau, Thomas,Holletz, Torsten,Cech, Dieter
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p. 387 - 388
(2007/10/03)
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