- Transition metal complex, polymer, mixture, composition and organic electronic device
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The invention discloses a transition metal complex, a polymer, a mixture, a composition and an organic electronic device. The transition metal complex has a structural general formula represented by achemical formula (1), and is simple to synthesize, novel in structure, relatively good in stability, long in service life and good in light emitting performance; the compound represented by the chemical formula (1) is convenient for realizing an efficient, high-brightness and high-stability OLED device, and a relatively good material option is provided for full-color display and illumination application.
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Paragraph 0419; 0423-0425
(2020/05/01)
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- IMIDAZO [1,5-A]PYRIMIDINYL CARBOXAMIDE COMPOUNDS AND THEIR USE IN THE TREATMENT OF MEDICAL DISORDERS
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The invention provides substituted imidazo[1,5-a]pyrimidinyl carboxamide and related organic compounds, compositions containing such compounds, medical kits, and methods for using such compounds and compositions to treat medical disorders, e.g., Gaucher disease, Parkinson's disease, Lewy body disease, dementia, or multiple system atrophy, in a patient. Exemplary substituted imidazo[1,5-a]pyrimidinyl carboxamide compounds described herein include substituted 2-heterocyclyl-4-alkyl-imidazo[1,5-a]pyrirnidine-8-carboxamide compounds and variants thereof.
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Paragraph 00516
(2017/11/04)
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- Imidazo [1,2-a] pyridine-6-boronic acid frequency ester and its derivatives preparation method
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The invention discloses preparation methods for imidazole[1,2-a]pyridine-6-boric acid pinacol ester and derivatives thereof. The preparation methods comprise a preparation method for imidazole[1,2-a]pyridine-6-boric acid pinacol ester, a preparation method for imidazole[1,2-a]pyridine-7-boric acid pinacol ester and a preparation method for imidazole[1,2-a]pyridine-8-boric acid pinacol ester. The imidazole[1,2-a]pyridine-6-boric acid pinacol ester and derivatives thereof prepared by using the preparation methods are used in the Suzuki coupling reaction for a coupling reaction with compounds like halides and TfO-R. According to a technical scheme in the invention, the preparation methods have the advantages of high reaction yield, easy purification, suitability for production, etc.
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Paragraph 0059-0064
(2016/10/17)
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- FATTY ACID SYNTHASE INHIBITORS
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This invention relates to novel spirocyclic piperidines according to Formula (I) which are inhibitors of fatty acid synthase (FAS), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.
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Page/Page column 58-59
(2014/01/18)
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- IMIDAZO [1,2-A]PYRIDINE DERIVATIVES AS FGFR KINASE INHIBITORS FOR USE IN THERAPY
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The invention relates to new bicyclic heterocyclyl derivatives of formula (I), to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
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Page/Page column 36
(2012/03/08)
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- IMIDAZOPYRIDINE DERIVATIVES AS INHIBITORS OF RECEPTOR TYROSINE KINASES
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The invention relates to new bicyclic heterocyclic derivative compounds, to pharmaceutical compositions comprising said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.
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- CYCLOHEXYLPYRAZOLE-LACTAM DERIVATIVES AS INHIBITORS OF 11-BETA-HYDROXYSTEROID DEHYDROGENASE 1
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The present invention discloses novel compounds of Formula (I): having 11β-HSD type 1 antagonist activity, as well as methods for preparing such compounds. In another embodiment, the invention discloses pharmaceutical compositions comprising compound
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Page/Page column 45
(2009/05/29)
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- IMIDAZO (1, 2-A) PYRIDINE COMPOUNDS AS VEGF-R2 INHIBITORS
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The present invention provides compounds that are inhibitors of VEGF-R2 of the formula: (I) and methods of using these compounds.
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Page/Page column 27
(2008/06/13)
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