Synthesis, cytotoxicity, and hemolytic activity of 6′-O-substituted dioscin derivatives
Dioscin derivatives (1-12) with a variety of substitutions at the 6′-OH of the chacotriosyl residue and the 3′,6′-anhydrosaponin derivatives (26, 30, and 32) were synthesized. All these derivatives showed much lower cytotoxicity than that of the parent di