cas 91539-82-1, 4-CHLORO-N,N-DIMETHYL-2-QUINAZOLINEMETHANAMINE | Articles data ｜lookchem

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91539-82-1

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A NEW "ONE FLASK" PREPARATION OF 2-ALKYLAMINO-4-CHLOROQUINAZOLINES FROM ORTHO AMINOBENZONITRILES AND PHOSGENIMINIUM SALTS
Phosgeniminium salts react easily with ortho amino-benzonitriles to give, selectively and quantitatively the corresponding 2-dialkylamino-4-chloroquinazolines.
Kokel, Bruno,Menichi, Gabriel,Hubert-Habart, Michel
p. 1557 - 1560
(2007/10/02)

A convenient novel "one pot" synthesis of quinazoline and benzoxazine derivatives from corresponding 2-amino and 2-hydroxybenzonitriles via phosgeniminium salt condensation
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Kokel, Bruno
p. 709
(2007/10/02)

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Chemical Properties

Boiling Point: 259.1°C at 760 mmHg
Flash Point:110.5°C
Density: 1.241g/cm³
Vapor Pressure: 0.0132mmHg at 25°C
Refractive Index: 1.624
PKA: 4.16±0.30(Predicted)
PSA: 29.02000
LogP: 2.34480

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