- 1,1,1-trichloroacetone preparation method
-
The invention provides a 1,1,1-trichloroacetone preparation method, which comprises the following steps: 1, adding monochloroacetone and an alkaline compound into a large amount of an aqueous solutionwithout other organic solvents; 2, forming an aqueous solution or a turbid liquid from the alkaline compound in water while stirring; 3, introducing chlorine gas while stirring until the solution isclear; and 4, in the whole reaction process, controlling the temperature at 0-25 DEG C. According to the invention, the method is simple in process, convenient to operate, high in yield and convenientfor industrial production, and can effectively control the acetone chlorination position, so that the generation of byproducts such as 1,1,3-trichloroacetone, tetrachloroacetone, pentachloroacetone and the like is reduced, and the purity of the prepared product is high and can reach more than 85% without further purification.
- -
-
Paragraph 0037-0044
(2020/03/12)
-
- Kinetics and mechanistic investigation into the degradation of naproxen by a UV/chlorine process
-
In this study, UV irradiation combined with chlorine (UV/chlorine) was used to degrade naproxen (NPX), a typical non-steroidal anti-inflammatory drug (NSAID) widely used for the treatment of symptoms associated with inflammation, in water. Compared with UV irradiation alone and direct chlorination, the UV/chlorine process shows a synergistic effect on NPX degradation. The effects of different factors, including the chlorine dose, solution pH, and the presence of Cl-, HCO3- or humic acid (HA), on NPX degradation in the UV/chlorine process were investigated. The results indicated that the degradation of NPX followed pseudo-first-order kinetics in all cases, and the rate constant increased as the chlorine dose increased and decreased as the pH increased. The effects of the water matrix on UV/chlorine treatment were species-dependent. The NPX degradation rate was inhibited by the presence of HCO3- and HA but significantly improved by Cl-. LC/MS/MS analysis indicated that NPX decomposition in the UV/chlorine process was associated with decarboxylation, demethylation and hydroxylation. These results indicate that the UV/chlorine process is a promising technology for the treatment of water polluted by emerging contaminants, such as NPX. However, UV/chlorine can notably enhance the formation of disinfection by-products compared to direct chlorination, which should be carefully considered when integrating this process into drinking water treatment schemes.
- Gao, Yu-Qiong,Gao, Nai-Yun,Chu, Wen-Hai,Yang, Qin-Lin,Yin, Da-Qiang
-
p. 33627 - 33634
(2017/07/12)
-
- 1,1,1-TRICHLOROPROPANONE: A MILD, SELECTIVE ACETYLATING AGENT
-
The use of the title compound in the acetylation of primary and secondary amines is described.
- Salim, Jose Roberto,Nome, Faruk,Rezende, Marcos Caroli
-
p. 1181 - 1188
(2007/10/02)
-
- Selected Methods for the Oxidation of 1,1,1-Trichloro-2-alkanols. An Efficient Modification Using Chromic Acid
-
The effectiveness of thirteen largely applied procedures has been checked in the oxidation of 1,1,1-trichloropropan-2-ol.A new, simple, and efficient modification using chromic acid has been found for the preparation of representative trichloromethyl ketones.
- Gallina, Carlo,Giordano, Cesare
-
p. 466 - 468
(2007/10/02)
-
- TRICHLOROMETHYLATION OF CARBONYL COMPOUNDS IN THE PRESENCE OF CROWN ETHERS
-
The reaction of potassium trichloroacetate with carbonyl compounds (aldehydes, acid anhydrides and chlorides) in acetonitrile in the presence of crown ethers leads to an increase of 11-19percent in the yield of the C-trichloromethylation products and reduces the reaction time by an order of magnitude.The macrocyclic perhydrodibenzo-18-crown-6-polyether, used as phase-transfer catalyst, is more effective than dibenzo-18-crown-6.
- Kyazimov, A. S.,Abdullabekov, I. M.,Karaev, S. F.
-
p. 1456 - 1458
(2007/10/02)
-
- SYNTHESIS OF SOME TRIS(TRIMETHYLSILYL)GERMYL COMPOUNDS
-
A variety of compounds containing the tris(trimethylsilyl)germyl group were prepared and characterized spectroscopically.Photolysis of adamantoyltris(trimethylsilyl)germane failed to yield the isomeric germene: in CCl4 the photolysis appeared to occur by a Norrish type 1 process.
- Brook, A. G.,Abdesaken, F.,Soellradl, H.
-
-
- CH3(.) vs. CF3(.): Relative Rates of Formation from β-Scission
-
The relative rates of formation of CH3(.) and CF3(.) from β-scission reactions of trifluoro-t-butoxy radical (1) have been measured to be about 10:1 by thermolysing both trifluoro-t-butyl hypochlorite (4) and bis(trifluoro-t-butyl) peroxydicarbonate (14) in CCl4 at 160 and 140 deg C.
- Jiang, Xi-Kui,Li, Xing-Ya,Wang, Ke-Yang
-
p. 745 - 746
(2007/10/02)
-
- Generation and Chemical Properties of Dicyclopropylcarbene. Ring Expansion, Chlorine Abstraction, C-H Insertion, and Alkene Addition Reactions
-
Thermolysis of 5,5-dicyclopropyl-2-methoxy-2-methyl-Δ3-1,3,4-oxadiazoline in solution at 80 deg C affords dicycloproylcarbene and methyl acetate in high yields.Dicyclopropylcarbene undergoes a variety of reactions including ring expansion to 1-cyclopropylcyclobutene, chlorine atom abstraction from carbon tetrachloride, and efficient insertion into the CH bond of chloroform.A rationale for the very different reactions of the carbene with CCl4 and CHCl3 is suggested.Carbene trapping by addition to tetrachloroethylene, using the oxadiazoline as the carbene source, is illustrated with the preparation of an adduct.
- Bekhazi, Michel,Risbood, Prabhakar A.,Warkentin, John
-
p. 5675 - 5679
(2007/10/02)
-
- Chlorination of Aliphatic Ketones in Methanol
-
The chlorination of aliphatic ketones in methanol has been examined.The product distributions in methanol differ substantially from those obtained by chlorination in carbon tetrachloride.The reaction in methanol favors addition of chlorine to the least substituted carbon α to the carbonyl group.The effect is especially pronounced if an α carbon bearing two substituents is present.The distribution of products is determined by the relative stability of the enol ethers formed from the ketone under the reaction conditions.
- Gallucci, R. R.,Going, R.
-
p. 2532 - 2538
(2007/10/02)
-
- Photolysis of Butane-2,3-dione in Fluorocarbon Solvents; a Chemically Induced Nuclear Polarization (CIDNP) Study
-
CIDNP observations of the polarized signals from products of radical reactions in solutions of neat butane-2,3-dione in perfluorocyclohexane and perfluorodecalin, and in solutions with added radical scavenger or hydrogen donor, are consistent with three primary processes.There are symmetric (probably) and unsymmetric fragmentation and hydrogen-abstraction by triplet butane-2,3-dione from the starting material, and each yields free radicals.In all solutions the mechanisms of ensuing reactions are suggested.In the presence of CCl4 and CCl3Br pair substitution effects dominate the CIDNP behaviour.When high concentrations of propan-2-ol are present evidence is given for reaction of the excited singlet state of the parent molecule.
- Broomhead, Eleanor J.,McLauchlan, Keith A.,Roe, Jonathan C.
-
p. 796 - 804
(2007/10/02)
-
