cas 921630-14-0, 2-Bromo-5-chloropyridine-4-carboxaldehyde | Articles data ｜lookchem

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921630-14-0

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AMINES
The invention relates to novel amine derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
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Page/Page column 10

(2009/04/24)

Primary Amines as Renin Inhibitors
The invention relates to novel primary amine derivatives and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
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Page/Page column 9

(2009/04/24)

Secondary Amines as Renin Inhibitors
The invention relates to novel secondary amine derivatives of formula (I) and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
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Page/Page column 16

(2009/07/18)

SECONDARY AMINES AS RENIN INHIBITORS
The invention relates to novel secondary amine derivatives of formula (I) and the use thereof as active ingredients in the preparation of pharmaceutical compositions. The invention also concerns related aspects including processes for the preparation of the compounds, pharmaceutical compositions containing one or more of those compounds and especially their use as inhibitors of renin.
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Page/Page column 44-45

(2010/11/28)

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Chemical Properties

Boiling Point: 281.936 °C at 760 mmHg
Flash Point:124.311 °C
Density: 1.8 g/cm³
Storage Temp.:2-8°C
Refractive Index: 1.632
PKA: -3.48±0.18(Predicted)
PSA: 29.96000
LogP: 2.31000

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