- 4-halogenated isoindoline hydrochloride preparation method
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The invention provides a 4-halogenated isoindoline hydrochloride preparation method. 2,3-dihalomethyl-3-halogenobenzene serving as a raw material is subjected to cyclization reaction to obtain a compound in a formula I, and a reaction formula is as shown
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- Preparation of dihydropyrrol derivatives as intermediates
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The invention is concerned with a new scalable process for the preparation of compounds of formula I comprising a new process for the preparation of the key intermediate, a dihydropyrrole derivative formula II or a salt thereof.
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Page/Page column 8
(2009/06/27)
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- NOVEL CYCLIC BORONATE INHIBITORS OF HCV REPLICATION
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Compounds of formula (I) or a salt thereof are provided; wherein R1, R2, R3, R4, R6, R8, R20, R30, Y, Z and n are as defined in the description. Uses of the compounds as medicaments, and in the manufacture of medicaments for treating viral infection, especially HCV infection are also disclosed. The invention further comprises processes to make these compounds and pharmaceutical formulations thereof.
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Page/Page column 68-69
(2009/05/29)
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