- PREPARING METHOD OF HYDRIZIDE COMPOUNDS
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The present invention relates to a method for preparing hydrazide and, more specifically, to a method for preparing a hydrazide derivative compound by reacting a hydrazine-carbon dioxide coupled compound with an organic acid or sulfonic acid compound.COPYRIGHT KIPO 2015
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Paragraph 0128; 0164-0165
(2017/01/02)
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- Synthesis of novel bis-1,3,4-thiadiazoles, bis-1,2,4-triazoles and their antimicrobial activity
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Condensation of scbacic acid dihydrazide (1) with aryl/alkyl isothiocyanates (2a-g) gives bis-(N-aryl/alkylthiocarbamido)-scbacic acid diamides (3a-g), which on reaction with o-phosphoric acid yields l,8-bis-(2-aryl/alkylamino-l,3,4-thiadiazol-5-yl)-octanes (4a-g). 1,8-Bis-(3-mercapto-4-aryl/alkyl-1,2,4-triazol-5-yl)-octanes (5a-g) were obtained by a similar condensation of compounds (3a-g) with aqueous KOH, which on reaction with ethyl iodide in the form of dihydroiodides have been isolated (6a-g). These on basification with aq. ammonia solution afforded free bases (7a-g). Compounds (4a-g) on benzoylation with benzoyl chloride and NaOH affords benzoyl derivatives (8a-g). The structures of all these compounds were confirmed on the basis of elemental analysis and spectral data and evaluated for their antimicrobial activity against gram positive and gram negative bacteria.
- Burghate, Megha K.,Burghate,Berad
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body text
p. 561 - 565
(2009/08/15)
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- Synthesis and characterization of N,N'-aliphatic dicarboxylbis(hydrazones)
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N,N'-Malonylbis-, N,N'-adipinylbis- and N,N'-sebacoylbis(hydrazones) 1 of various aldehydes and ketones have been prepared and characterized by elemental analyses, melting points, and 1H NMR and IR spectral data.
- Amanulla, S.,Jain, S. R.
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p. 687 - 690
(2007/10/03)
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