Total synthesis of the cytotoxic alkaloid luotonin A
The structure of luotonin A was unambiguously confirmed by total synthesis. Deprotonation of 3-oxo-1H-pyrrolo[3,4-b]quinoline gave an anion which was coupled with 2-sulfinylaminobenzoyl chloride (prepared by reaction of anthranilic acid with thionyl chlor
Wang, Haishan,Ganesan
p. 9097 - 9098
(2007/10/03)
Total synthesis of nothapodytine b and (-)-mappicine
Concise total syntheses of naturally occurring nothapodytine B (1, mappicine ketone) and ( - )-mappicine (3) are detailed. The approach is based on the implememation of a room-temperature, inverse electron demand Diels-Alder reaction of the N-sulfonyl-1-aza-1.3-butadiene 11 for assemblage of a pyridone 1) ring precursor central to the structure. A Friedlander condensation is utilized for constructing the AB ring system of 1 and 3. An acid-catalyzed reaction sequence is used to accomplish a deprotection with subsequent ring-closure for introduction of the C ring in a single step.
Boger, Dale L.,Hong, Jiyong
p. 1218 - 1222
(2007/10/03)
2-(2-imidazolin-2-yl)-pyridines and quinolines, process and intermediates for the preparation thereof, and use of said compounds as herbicidal agents
There are provided novel 2-(2-imidazolin-2-yl)pyridine and quinoline compounds, a process and intermediate compounds for the preparation thereof, and a method for controlling a wide variety of annual and perennial plant species therewith.
-
(2008/06/13)
Process for the preparation of 2,3-quinolinedicarboxylic acids
There is provided a novel process for the preparation of a substituted or unsubstituted 2,3-quinolinedicarboxylic acid, utilizing as the starting material, 2-methyl-3-quinolinecarboxylic acid or 3-methyl-2-quinolinecarboxylic acid or the alkyl ester of either of the above compounds.
-
(2008/06/13)
More Articles about upstream products of 92513-28-5