cas 926276-19-9, (1S,3aR,6aS)-2-[(2S)-2-[[(2S)-2-Cyclohexyl-2-[(2-pyrazinylcarbonyl)amino]acetyl]amino]-3,3-dimethyl-1-oxobutyl]octahydrocyclopenta[c]pyrrole-1-carboxylic acid tert-butyl ester | Articles data ｜lookchem

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926276-19-9

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PROCESS FOR THE SYNTHESIS OF TELAPREVIR, OR PHARMACEUTICALLY ACCEPTABLE SALTS OR SOLVATES AS WELL AS INTERMEDIATE PRODUCTS THEREOF
The invention relates to a process for the preparation of telaprevir, or a pharmaceutically acceptable salt or solvate thereof, wherein the process requires a smaller number of process steps and/or does not require the use of toxic and instable compounds compared to the known processes. Another embodiment refers to telaprevir, or a pharmaceutically acceptable salt or solvate thereof as well as to intermediate products for preparation of the same, wherein the afore-mentioned products are obtained by the process described herein.
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Page/Page column 19-20

(2013/09/26)

Processes and intermediates
The invention relates to compounds and processes useful for the preparation of protease inhibitors, particularly serine protease inhibitors. The protease inhibitors are useful for treatment of HCV infections.
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Page/Page column 21; 47-48

(2010/11/26)

More Articles about upstream products of 926276-19-9

More Articles about downstream products of 926276-19-9

402958-98-9
(1S,3aR,6aS)-2-((S)-2-((S)-2-cyclohexyl-2-(pyrazine-2-carboxamido)acetamido)-3,3-dimethylbutanoyl)octahydrocyclopenta[c]pyrrole-1-carboxylic acid

Chemical Properties

Boiling Point: 779.1±60.0 °C at 760 mmHg
Flash Point:425.0±32.9 °C
Density: 1.2±0.1 g/cm³
Solubility:Dichloromethane
Storage Temp.:-20°C Freezer, Under inert atmosphere
PSA: 137.57000
LogP: 5.00800

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