Phenazopyridine cocrystal and salts that exhibit enhanced solubility and stability
One phenazopyridine monohydrate (1?H2O), one cocrystal of phenazopyridine with phthalimide (2), and three salts of phenazopyridine with benzoic acid (3), 4-hydroxyphenylacetic acid (4), and scaaharin (5) were synthesized, and their structures w
Tao, Qian,Chen, Jia-Mei,Ma, Lei,Lu, Tong-Bu
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p. 3144 - 3152
(2012/08/14)
PHENAZOPYRIDINE COMPOUNDS
The present invention is directed to substituted phenazopyridines represented by Formula I. The present invention also relates to the discovery that compounds of Formula I have increased bioavailability as compared to unconjugated phenazopyridine.