- MULTIBIOTIC AGENTS AND METHODS OF USING THE SAME
-
Multibiotic agents are disclosed. The multibiotic agents may contain two or more moieties linked through bonds cleavable in vivo. The bonds cleavable in vivo can be ester bonds, amide bonds, azo bonds, glycosidic bonds, carbonate linkers, or carbamate linkers. The moieties can be alcohol cores, amine cores, and/or acyls. Also disclosed are compositions containing multibiotic agents and methods of using the multibiotic agents.
- -
-
Page/Page column 114
(2019/01/06)
-
- Preparation method of D-panthenyl triacetate
-
The invention discloses a preparation method of D-panthenyl triacetate. D-panthenyl triacetate is prepared from D-panthenol and acetic anhydride through reaction under the absent condition of the catalysis of a solvent and 4-dimethylaminopyridine, wherein the reaction temperature is 60 DEG C to 90 DEG C; after the reaction step, a product is obtained through the steps of acetic acid removal, extraction, washing, drying and reduced pressure distillation. According to the invention, a homogeneous reaction is adopted; a catalyst is not needed to be fixed on a polymer, which can greatly shorten the reaction time, the yield is higher than 90 percent, and the product quality is guaranteed.
- -
-
Paragraph 0015
(2016/10/10)
-
- Selective synthesis of panthenyl esters by a kinetically controlled enzymatic process
-
Panthenyl esters (panthenyl monoacetate and panthenyl diacetate) were synthesized in high yields (≈100%) by a kinetic reaction control using a commercial immobilized Candida Antarctica lipase B (Novozyme 435) in acetonitrile. The enzyme showed excellent synthetic activity, regioselectivity, and operational stability under the conditions used.
- De Diego, Teresa,Manjon, Arturo,Iborra, Jose L.
-
p. 175 - 180
(2013/09/12)
-