Hypervalent Iodine Oxidation of Flavanone. Synthesis of cis- and trans-3-Hydroxyflavanones
The synthesis of cis-3-hydroxyflavanone (3a) from flavanone (1) via acid-catalyzed hydrolysis of dimethyl acetal 4 formed by C6H5I(OAc)2-KOH/CH3OH oxidation is described.Unger more vigrous hydrolytic conditions isomerization accompanies hydrolysis of 4 wi
Hypervalent Iodine Oxidation of α,β-Unsaturated Ketones: Chromone, Flavone, Chalcone, and Flavanone
Reaction of the title compounds with PhI(OAc)2 and MeOH-KOH leads to α-hydroxydimethylacetal β-methoxy products regiospecifically and stereospecifically, as demonstrated by X-ray diffraction.
Moriarty, Robert M.,Prakash, Om,Freeman, Wade A.
p. 927 - 929
(2007/10/02)
More Articles about upstream products of 94137-50-5