SUBSTITUTED PHENYLENEDIAMINES AS INHIBITORS OF THE INTERACTION BETWEEN MDM2 AND P53
The present invention provides compounds of formula (I), their use as an inhibitor of a p53-MDM2 interaction as well as pharmaceutical compositions comprising said compounds of formula (I).
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Page/Page column 31
(2009/04/25)
Enantioselective synthesis of protected amines by the catalytic asymmetric addition of hydrazoic acid to ketenes
(Chemical Equation Presented) A-mine of possibilities: An effective method for the conversion of achiral ketenes into enantioenriched protected amines was developed by tuning the structure and reactivity of a catalyst on the basis of a mechanistic hypothe
Dai, Xing,Nakai, Takashi,Romero, Jan A. C.,Fu, Gregory C.
p. 4367 - 4369
(2008/03/12)
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