Synthesis of Aza-Heteroaromatic Dithiocarbamates via Cross-Coupling Reactions of Aza-Heteroaromatic Bromides with Tetraalkylthiuram Disulfides
The preparation of various aza-heteroaromatic dithiocarbamates from aza-heteroaromatic bromides and tetraalkylthiuram disulfides is reported. The transformation provides a convenient procedure, with good yields and functional group tolerance to various important nitrogen-containing heteroaromatic dithiocarbamates such as benzothiazole, quinoline, pyridine, and pyrazine motifs. This protocol allows the facile synthesis of some potential biologically active compounds.
Heterocyclic dithiocarbamate compound and preparation method thereof
The invention relates to a heterocyclic dithiocarbamate compound and a preparation method thereof. The heterocyclic dithiocarbamate compound is of a structure of formula (1) or (2) as shown in the description. The heterocyclic dithiocarbamate compound provided by the invention is prepared from benzothiazole or furfuran as a mother ring, types of the heterocyclic dithiocarbamate compound can be further enriched, and related products have wide application prospects in fields such as antibacterial agents, insecticides, medicine intermediates and perfume precursor compounds.