Bay-Region Annulative π-Extension of o-Iodobiphenyls with Aliphatic Anhydrides Catalyzed by Pd(OAc)2
Bay-region annulative π-extension of o-iodobiphenyls with aliphatic anhydrides was developed. Many o-iodobiphenyls and aliphatic anhydrides can react well under the optimized conditions. A lot of phenanthrol derivatives can be efficiently prepared by this approach. The control experiments support that dibenzopalladacyclopentadienes may be the reaction intermediates.
The direct irradiation of iodoalkenes leads to the formation of carbon-centered radical by homolysis of the C-I bond. The photoreaction is used in cyclizations with formation of six membered rings.
Campos-Gómez, Esther,Campos, Pedro J.,González, Héctor F.,Rodríguez, Miguel A.