- Process for producing α,β-unsaturated aldehydes
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The present invention relates to a process for producing an α,β-unsaturated aldehyde which comprises subjecting an allyl-hexamethylenetetraammonium derivative to hydrolysis in water and an organic solvent homogeneously immiscible with water. The resulting α,β-unsaturated aldehyde is useful as medicaments, flavorings, etc., or as raw materials for their production.
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- Synthesis of New Aromatic Retinoid Analogues by Low-Valent Titanium Induced Reductive Elimination
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The low-valent titanium reductive elimination reaction, already applied to the stereospecific synthesis of vitamin A and 13-cis-retinol, was used to prepare several retinoic acid analogues in the all-trans configuration or in the 13-cis configuration.This highly stereospecific trans-diene formation allowed an improved synthesis of the title compounds without any purification of the intermediates before the final stage.
- Solladie, Guy,Girardin, Andre,Lang, Gerard
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p. 2620 - 2628
(2007/10/02)
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