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CYCLAZOCINE

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Name

CYCLAZOCINE

EINECS 222-689-9
CAS No. 3572-80-3 Density 1.123g/cm3
PSA 23.47000 LogP 3.26430
Solubility N/A Melting Point 201-204°
Formula C18H25 N O Boiling Point 399.2°Cat760mmHg
Molecular Weight 271.403 Flash Point 188.7°C
Transport Information N/A Appearance N/A
Safety A poison by subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Used in the treatment of narcotic addiction. When heated to decomposition it emits toxic fumes of NOx. Risk Codes N/A
Molecular Structure Molecular Structure of 3572-80-3 ((+)-CYCLAZOCINE) Hazard Symbols N/A
Synonyms

Cyclazocine;NSC 107429; Win 20740

Article Data 6

CYCLAZOCINE Chemical Properties

Product Name: Cyclazocine (CAS NO.3572-80-3 )


Molecular Formula: C18H25NO
Molecular Weight: 271.44g/mol
Mol File: 3572-80-3 .mol
Boiling point: 399.2 °C at 760 mmHg
Flash Point: 188.7 °C
Density: 1.123 g/cm3
Surface Tension: 45 dyne/cm
Enthalpy of Vaporization: 67.53 kJ/mol
Vapour Pressure: 6.04E-07 mmHg at 25°C
XLogP3: 2.6
H-Bond Donor: 1
H-Bond Acceptor: 2

CYCLAZOCINE Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 28mg/kg (28mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 165, Pg. 112, 1967.
mouse LD50 subcutaneous 150mg/kg (150mg/kg)   Arzneimittel-Forschung. Drug Research. Vol. 26, Pg. 2009, 1976.
mouse LDLo intraperitoneal 10mg/kg (10mg/kg)   Research Communications in Chemical Pathology and Pharmacology. Vol. 17, Pg. 255, 1977.
rat LD50 intravenous 32mg/kg (32mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 165, Pg. 112, 1967.
rat LD50 subcutaneous 310mg/kg (310mg/kg)   Journal of Pharmacology and Experimental Therapeutics. Vol. 143, Pg. 141, 1964.

CYCLAZOCINE Safety Profile

A poison by subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Used in the treatment of narcotic addiction. When heated to decomposition it emits toxic fumes of NOx.

CYCLAZOCINE Specification

 Cyclazocine ,its CAS NO. is 3572-80-3 ,the synonyms is 2,6-Methano-3-benzazocin-8-ol, 3-(cyclopropylmethyl)-
1,2,3,4,5,6-hexahydro-6,11-dimethyl- ; 2-Cyclopropylmethyl-2'-hydroxy-5,9-dimethyl-6,7-benzomorphan ; 2-Cyclopropylmethyl-5,9-dimethyl-2'-hydroxy-6,7-benzomorphan ; 3-(Cyclopropylmethyl)-1,2,3,4,5,6-hexahydro-6,11-dimethyl-
2,6-methano-3-benzazocin-8-ol ; 3-Cyclopropylmethyl-6(eq),11(ax)-dimethyl-2,6-methano-3-benzazocin-8-ol ; Ciclazocina ; Cyclazocine ; Cyclazocinum .

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