Basic information of :

(1)CAS No.: ;
(2)Other Names: NRG-1;
(3)PubChem CID: 11243002;
(4)ChemSpider: 9418039;
(5)Formula: C₁₉H₂₃NO;
(6)Mol. mass: 281.391 g/mol.

Naphyrone is a drug derived from pyrovalerone that acts as a triple reuptake inhibitor, producing stimulant effects and has been reported as a novel designer drug. The drug has been marketed under the name NRG-1, although only a minority of samples of substances sold under this name have been found to actually contain naphyrone.

Naphyrone emerged as a new legal high in the United Kingdom only months after the ban of similar drug mephedrone. The Medicines Act prevented naphyrone from being sold for human consumption, and therefore it was sometimes sold as 'pond cleaner' or as another substance not normally consumed by humans.

As a triple reuptake inhibitor, naphyrone has been shown in vitro to affect the reuptake of the neurotransmitters serotonin, dopamine and norepinephrine by interacting with the serotonin transporter (SERT), dopamine transporter (DAT), and norepinephrine transporter (NET).