Chembench is a free portal that enables researchers to mine available chemical and biological data. Chembench can help researchers rationally design or select new compounds or compound libraries with significantly enhanced hit rates in screening experiments.

It provides cheminformatics research support to molecular modelers, medicinal chemists and quantitative biologists by integrating robust model builders, property and activity predictors, virtual libraries of available chemicals with predicted biological and drug-like properties, and special tools for chemical library design. Chembench was initially developed to support researchers in the Molecular Libraries Probe Production Centers Network (MLPCN) and the Chemical Synthesis Centers.