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Cas Database |
| Name |
Dexchloropheniramine maleate |
EINECS | 219-450-6 |
| CAS No. | 2438-32-6 | Density | N/A |
| PSA | 90.73000 | LogP | 3.53040 |
| Solubility | N/A | Melting Point |
112-115 °C(lit.) |
| Formula | C16H19ClN2•C4H4O4 | Boiling Point | 379 °C at 760 mmHg |
| Molecular Weight | 390.867 | Flash Point | 183 °C |
| Transport Information | UN 2811 6.1/PG 3 | Appearance | White solid |
| Safety | 36/37/39-45 | Risk Codes | 25 |
| Molecular Structure |
|
Hazard Symbols |
 T
|
| Synonyms |
(+)-2-(p-Chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridine maleate (1:1);D-Chlorpheniramine maleate;Polaramine (TN);(+)-Chlorpheniramine maleate;Polaramine;(gamma-(4-Chlorophenyl)-pyridine-2-propyl)(dimethyl)ammonium hydrogen (Z)-maleate;but-2-enedioic acid; (3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-yl-propan-1-amine;Pyridine, 2-(p-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)-, maleate (1:1), (+)-;S-(+)-Chlorpheniramine maleate; |
Article Data | 7 |
Dexchloropheniramine maleate Chemical Properties
MF: C20H23ClN2O4
MW: 390.86
EINECS: 204-037-5
Flash Point: 183 °C
Melting Point: 112-115 °C(lit.)
Enthalpy of Vaporization: 62.7 kJ/mol
Vapour Pressure: 6.04E-06 mmHg at 25°C
Boiling Point of Polaramine maleate (2438-32-6): 379 °C at 760 mmHg
IUPAC Nsme: (Z)-but-2-enedioic acid ; (3S)-3-(4-chlorophenyl)-N,N-dimethyl-3-pyridin-2-ylpropan-1-amine
Synonyms: (+)-Chlorpheniramine maleate salt ; Dexchloropheniramine maleate ; Dexchlorpheniramine maleate ; D-chlorpheniramine maleate ; Gamma-[4-chlorophenyl]-N,N-dimethyl-2-pyridinepropanamine maleate salt ; (+)-2-(P-chloro-alpha-(2-(dimethylamino)ethyl)benzyl)pyridinemaleate ; (S)-(+)-Chlorpheniraminemaleate ; Dextrochlorpheniraminemaleate
Following is the molecular structure of Polaramine maleate (2438-32-6):
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Dexchloropheniramine maleate Uses
Polaramine maleate (2438-32-6) is a cholinergic drugs treating simple conjunctivitis. Preparations for the drops.
Dexchloropheniramine maleate Toxicity Data With Reference
| 1. | orl-rat LD50:267 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. | ||
| 2. | ipr-rat LD50:119 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. | ||
| 3. | orl-mus LD50:189 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. | ||
| 4. | ipr-mus LD50:117 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. | ||
| 5. | ivn-mus LD50:28 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. | ||
| 6. | orl-gpg LD50:240 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 124 (1958),347. |
Dexchloropheniramine maleate Safety Profile
Poison by ingestion, intravenous, and intraperitoneal routes. When heated to decomposition it emits toxic fumes of Cl− and NOx.
Safety Information of Polaramine maleate (2438-32-6):
Hazard Codes: T
T: Toxic .gif)
Risk Statements: 25
25: Toxic if swallowed
Safety Statements: 36/37/39-45
36/37/39: Wear suitable protective clothing, gloves and eye/face protection
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR: UN 2811 6.1/PG 3
WGK Germany: 3
RTECS: US6504000
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